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Celiac Disease: One of the Most Common Lifelong Disorders in the US and Europe!

What is the Difference Between Celiac Disease and Non-Celiac Gluten Sensitivity?

Do Gluten-Related Disorders Primarily Affect the Gut?

Why Did Dr. O’Bryan First Start Working With Gluten-Related Disorders?

Negative Celiac Blood Tests But Feel Better on a Gluten-Free Diet? Why Tests Are Often Wrong

Diamidated Gliadin: A More Sensitive Blood Test for Partial Villous Atrophy in Celiac Disease

Diagnosing the Early Stages of Celiac Disease: Biopsy No Longer a Gold Standard

What Are the Possible Signs of Celiac Disease?

It Can Take 8-11 Years For Patients to be Diagnosed with Celiac Disease AFTER Symptoms Start

Who Should Be Tested For Celiac Disease?

Why Blood Tests For Celiac Disease Can Be Wrong Up To 70% Of The Time

The Benefits of a Gluten-Free Diet

Celiac Disease: Even a Milligram of Gluten a Day Can Prevent Mucosal Recovery

Can a Person With a Gluten-Related Disorder Have Just a Little Gluten?

Celiac Disease and Related Neurological and Psychiatric Disorders

Family History of ANY Autoimmune Disease? Consider a Gluten-Related Disorder

Lack of Blood Flow to the Brain in Celiac Disease Can Lead to Anorexia Nervosa

A Gluten-Related Disorder Can Manifest With ONLY Neurological Symptoms

The Mechanism of Muscle Pain and Damage in Sensitivity to Gluten

Migraines and Non-Celiac Gluten Sensitivity

Celiac Disease and Dental Enamel Defects

Sensitivity to Gluten Can Be Primarily or Exclusively a Neurological Disorder

Lack of Blood Flow to the Brain in Celiac Disease

Celiac Disease and Alzheimer’s

Three-Quarters of Newly Diagnosed Celiac Patients Had a Lack of Blood Flow to the Brain

Gluten-Free Diet Associated With Regain in Bone Mineral Density in Celiac Patients With Osteopenia

Untreated Celiac Disease Dims the Brain, Can Lead to Underachievement!

Celiac Disease’s Neuro. Symptoms Can Include ADHD, Headache, Ataxia, Epilepsy, Learning Disabilities

What Effect Can Cows Milk Have on Celiac Patients?

Celiac Disease, Lack of Blood Flow to the Brain, and Migraines

Why Sensitivity to Gluten Can Lead to Muscle Pain (Myopathy)

Myth: People With Celiac Disease Are Always Underweight. Fact: Celiacs May Be Overweight or Obese

Celiac Disease and Liver Disease

Celiac Disease and Delayed Growth in Children

Undiagnosed Silent Celiac Disease and Underachievement in Life

A Large Forehead Can Be a Sign of Celiac Disease

Numbness and Tingling (Peripheral Neuropathy): Most Common Neurological Symptom of Celiac Disease

Dermatitis Herpetiformis: A Gluten-Related Disorder

Silent Celiac Disease and Disruptive Disorders, ADHD and Depression in Children and Adolescents

Transverse Leukonychia (White Bands on Fingernails)

Vitamin D Deficiency and Increased Risk of Inflammatory Bowel Disease

Untreated Celiac Disease and Vitamin K Deficiency (Easy Bruising, Nosebleeds, Angular Cheilitis)

The Inflammatory Cascade in Gluten Sensitivity: A Life of Its Own

Gluten-Related Disorders and Inflammation in the Brain: Treat the Fire Not the Smoke!

The Benefits of Colostrum: the Development of the Immune System & Correcting Intestinal Permeability

Colostrum Helps Restore Gut Integrity and Modulates the Immune System

Colostrum and the Immune System

Dr. O’Bryan Interviews a 10-Year Old About Being Gluten- and Dairy-Free

The Gluten Summit, Available NOW!

The Gluten Summit: Summary with Dr. Tom O’Bryan and Sean Croxton of Underground Wellness

“Now That You Know, Where Do You Go?” Webinar. The Follow-Up to the Gluten Summit, Available Now!

Sean Croxton and Dr. O’Bryan: How to Avoid Gluten in Restaurants

Sean Croxton and Dr. O’Bryan: Summary of the Gluten Summit

Sean Croxton and Dr. O’Bryan: Is Gluten Causing Your Headaches?

Sean Croxton and Dr. O’Bryan: the Gluten-Autoimmune Connection

Sean Croxton and Dr. O’Bryan: How LPS Toxicity Can Wreak Havoc on Your Health

Sean Croxton and Dr. O’Bryan: How to Detect Gluten Sensitivity!

Sean Croxton and Dr. O’Bryan: Celiac Disease & Gluten Sensitivity

Dr. Rodney Ford’s Response to Dr. O’Bryan

Your Condition Could Be Gluten-Related

A Simple Explanation of Gluten

Find Help Going Gluten-Free

What Are the Two Most Common Triggers of Intestinal Permeability (“Leaky Gut”)?

What is the Difference Between Celiac Disease and Gluten Sensitivity?

‘The Conundrum of Gluten Sensitivity vs. Celiac Disease’ on the Wellness Wednesdays Show

Ben Coomber Interviews Dr. O’Bryan on Gut Health

‘Is Gluten the Cause of your Health Problems?’ Wendy Myers Interviews Dr. O’Bryan

Gluten Expert Panel: Dr. Tom O’Bryan, Nora Gedgaudas and Steve Wright

The Conundrum of Gluten Sensitivity Part 1: Functional Medicine Study Group, 2011

The Conundrum of Gluten Sensitivity Part 2: Functional Medicine Study Group, 2011

The Conundrum of Gluten Sensitivity Part 3: Functional Medicine Study Group, 2011

Jonathan Bailor Interviews Dr. O’Bryan

The Conundrum of Gluten Sensitivity vs. Celiac Disease at Hawthorn University

Overview of the Gluten Summit With Dr. O’Bryan and Sean Croxton

Dr. O’Bryan Interviewed By Josh Gitalis

Dave Asprey the Bulletproof Executive Interviews Dr. O’Bryan on Gluten Sensitivity, Celiac Disease & Bulletproofing Your Gut

Dr. Deanna Minich interviews Dr. O’Bryan about Gluten Sensitivity and Celiac Disease

Dr. O’Bryan interviewed by Maximus Mark

American Nutrition Association: Take Gluten-Free Living to the Next Level, Part 1

American Nutrition Association: Take Gluten-Free Living to the Next Level, Part 2

The Conundrum of Gluten Sensitivity, Why the Tests are Often Wrong. Purring vs Rumbling

Many of us believe that the toxic peptides of gluten found in wheat, rye and barley may detrimentally affect any tissue in the body and are not restricted to the intestines. As a matter-of-fact, one of the ‘mantras’ of the Gluten Sensitivity network comes from an 8-yr old article: “That gluten sensitivity is regarded as principally a disease of the small bowel is a historical misconception.1” There is a key word in this statement which I suspect was an emphasis of the Author’s message and sets the tone for this article (and this Network Movement). That key word is ‘principally’. Is Gluten Sensitivity ‘principally’ a disease of the small intestine? Point-blank answer – No it is not. For every Gluten Sensitive patient with the symptoms of an enteropathy (Classic Celiac Disease), there are 8 with no GI symptoms. Read Full Article Here…

Gluten Sensitivity without Celiac Disease: It is a Fad?

THE MYTH: Gluten Sensitivity without Celiac Disease is a Fad

 THE TRUTH: Non-celiac gluten sensitivity (NCGS) is not only real, but experts also tell us it is the most common (and non-recognized) condition in the family of gluten-related disorders. Read the full article Here.





Top Three Tips for Better Health

It can be a challenge to establish good health habits with today’s hectic lifestyle. And if you’re one of the millions living with a chronic condition, it can be even harder. Too often we neglect our health until a health crisis — such as celiac disease or gluten sensitivity — forces us to examine how we live and make some serious changes. The practices we develop in this space require time and effort, but the rewards are tremendous. Positive lifestyle changes can propel you to a healthier, happier place than you have ever known. Read More

News regarding Pediatric Autoimmune Disease:

Hypergammaglobulinemia in the pediatric population as a marker for underlying autoimmune disease: a retrospective cohort study.


Background: The significance of hypergammaglobulinemia as a marker of immune activation is unknown, as a differential diagnosis for hypergammaglobulinemia in children has not been adequately established. The goal of this study was to identify conditions associated with hypergammaglobulinemia in children, with the hypothesis that elevated immunoglobulin levels may precede or predict the development of autoimmune conditions.

Methods: We reviewed the medical records for all children with IgG level ≥2000 mg/dL treated at a tertiary care children’s hospital from January 1, 2000 through December 31, 2009. We compared clinical and laboratory features of these patients, and developed an algorithm to predict the likelihood of underlying autoimmunity based on these characteristics.

Results: After excluding children who had received IVIG, a total of 442 patients with hypergammaglobulinemia were identified. Of these, nearly half had autoimmune conditions, most frequently systemic lupus erythematosus and lupus-related disorders. Autoimmune gastrointestinal disorders such as inflammatory bowel disease were also common. Infectious diseases were the next largest category of diseases, followed with much less frequency by malignant, drug-related, and other conditions. In comparison with non-autoimmune conditions, patients with autoimmune disease had higher IgG levels, lower white blood cell counts, lower hemoglobin values, and lower C-reactive protein (CRP) levels. Multivariable logistic regression confirmed that CRP (P = 0.002), white blood cell count (P < 0.001), hemoglobin (P = 0.015), and female gender (P < 0.001) are independent risk factors for autoimmune disease in patients with high IgG levels.

Conclusions: In a cohort of pediatric patients at a tertiary care children’s hospital, hypergammaglobulinemia was most commonly associated with autoimmune diseases. In female patients with hypergammaglobulinemia, the presence of leukopenia, anemia, and normal CRP was 95% predictive of underlying autoimmune disease. You can read the Full Article Here.

Review all 19 research articles from our Livestream Event: Gluten Sensitivity: Fantasy, Fad, Fiction or Fact?  

Read the full article Here.

Dr. Fasano on the future of celiac disease

What he thinks about the biopsy, a .pill, the economy, an Increase in CD … and GF pizza By Amy Ratner

SEVEN YEARS AGO, I sat down for an in-depth interview with Alessio Fasano, MD, director of the Center for Celiac Research, shortly after his landmark study that detennined one in 133 people has celiac disease. There was great excitement at that time about all the things likely to happen now that it was clear celiac disease was much more common than anyone thought. We met that time in his office at the University of Maryland School of Medicine in downtown Baltimore. It seemed fitting to be talking about the study and other cutting edge research not far from the celiac center clinic lab where much ofthe work was going on. This time we talked over lunch in a noisy pizza parlor that has gluten-free pizza on its menu-something we could only have dreamed about in 2003. Fasano, a prolific celiac researcher, writer, ambassador and advocate, had just returned from an ambitious trip to Europe where he traveled between Finland, Germany and his native Italy. In Finland, he donned a topcoat with tails and a very tall hat to participate in formal proceedings where a fellow researcher was defending his thesis on the role the biopsy plays in the diagnosis of celiac disease. Read More

Reintroduce Gluten : Gluten Sensitivity Testing

Question: Do I have to reintroduce gluten in order to have an accurate gluten sensitivity test done?

Answer: Yes and No Read More

Gluten Sensitivity: Real Disorder, Real Symptoms

There’s a lot of confusion about gluten sensitivity. Some say it doesn’t exist. Others think going gluten free without celiac disease is unnecessary and is just a fad. But science now confirms what glutensensitive patients and their doctors have known for years: Gluten sensitivity is a real disorder with defined symptoms that can affect any part of the body.  Read More

Predicting and Preventing Autoimmunity, Myth or Reality?

Taken as a group, autoimmune diseases are the third leading cause of morbidity and mortality in the industrialized world, only surpassed by cancer and heart disease. Many autoimmune diseases are chronic diseases that progress over the course of years and are characterized by the presence of autoantibodies that precede the overt disease. Autoantibodies may also predict specific clinical manifestation, disease severity, and rate of progression, as well as specific clinical phenomena, such as autoimmune pregnancy loss. Read More

The Mosaic of Autoimmunity: Prediction, Autoantibodies, and Therapy in Autoimmune Diseases – 2008

The most significant development in our understanding of autoimmunity in the last 5 years relates to our ability to predict autoimmune diseases. Predictivity of autoimmunity For more than two decades, the detection of serum autoantibodies has been used for the diagnosis and classification of autoimmune diseases. In addition, some autoantibodies have a prognostic significance or are used as markers for disease activity. In recent years a new piece in the mosaic of autoimmunity has clearly emerged – namely, the predictive value of autoantibodies. Read More

Celiac Disease

Dr. O’Bryan discusses the subject of Celiac disease on “To Your Health”, with Ann Goldeen.

June 8th, 2010

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Celiac Disease

Dr. O’Bryan discusses celiac disease on “Good News Health (Bill in the morning)”, with host Bill Swail.

February 20th, 2010

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Celiac Disease

Dr. O’Bryan discusses celiac disease – how to identify and treat – with host Charles Green, on ‘Better Health Talk Radio’. June 9th, 2009

Autoimmune Diseases

Dr. Tom discusses autoimmune diseases on “Dishing Up Nutrition, hosted by Dar and Cassie”.

October 17th, 2009

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Dr. O’Bryan discusses the subject of autoimmunity on “Health Insight”, with TJ Harrington.

October 17th, 2009

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Gluten Sensitivity

Dr. O’Bryan discusses the subject of gluten sensitivity with guest host Dr. Victor Carsrud on “Let’s Get Healthy with Bill Swail”.

June 19th, 2010

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Gluten Intolerance

Dr. O’Bryan discusses the subject of gluten intolerance on “To Your Health”, with Ann Goldeen.

June 8th, 2010.

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Healthy Choices from the People’s Pharmacy

Dr. O’Bryan discusses the subject of gluten sensitivity with Ray Solano on “Healthy Choices from the People’s Pharmacy”, in Austin, Texas.

February 20th, 2010.

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Health Insight

Dr. O’Bryan discusses the subject of gluten sensitivity on “Health Insight”, with TJ Harrington.

November 15th, 2008.

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At Last. Accurate, Sensitive, Dependable, Laboratory Identification of Gluten Sensitivity, Celiac Disease, Intestinal Permeability and the Auto-immune process.  Clinical Rounds with Designs For Health – A Webinar for Healthcare Professionals.

October 29, 2010

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