ALCAT Celiac, IBS, and Crohn’s Array (CICA): Genetic Testing Only Cheek

Cheek Swab Collection Kit

HLA typing for celiac disease: HLA-DQ2.5 and HLA-DQ8; Genetic Markers for Crohn's: ATG16L1 and NOD2

Strong evidence shows that in order to develop celiac disease, a person must have one or both of two genotypes known as HLA-DQ2.5 and HLA-DQ8. More than 95% of patients with celiac disease have at least one of the two genetics. Most celiac patients (more than 90%) carry the DQ2 genetic.

Crohn’s disease is triggered by a variety of environmental and genetic factors. It is described as a chronic inflammatory bowel disease (IBD) caused by a dysregulation of the immune response to intestinal flora and in parallel, accompanied by a defect of the epithelial barrier. The predominant genetic markers are:

  • NOD2/CARD15 associated with the innate immune system and the activation of nuclear factor кB (NF- кB).
  • T300A mutation in the ATG16L1 gene increases its susceptibility to degradation by Caspase 3 and thus is associated with autophagy.

Old Price: $395.00

Price: $295.00

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